The Gonda Building is a medical building owned by the Mayo Clinic in Rochester, Minnesota, and designed by Ellerbe Becket Architects and Engineers.It rises 305 feet (93 m) in 21 floors, and was completed in 2001.The Gonda building was the largest building project in the Mayo Clinic’s history, the Leslie & Susan Gonda Building was constructed in three phases to a height of 21 stories. It has the capability to add 10 more floors. Located at the heart of the campus, Gonda is the centerpiece of Mayo’s integrated practice.The Gonda Building is physically conjoined on its South side to the Mayo Building although the floors do not match perfectly.
Planned Parenthood is the nation's leading sexual and reproductive health care provider and advocate, and has been providing trusted health care for nearly 100 years. Learn more.
WE ARE A MAYO CLINIC INSURANCE CHIROPRACTIC PROVIDER!! Established over 34 years ago, this business has maintained a level of excellence like no other. The expansion of the building in 2014 made Northgate Chiropractic Clinic the largest Chiropractic Facility in Rochester as well as the one with the most convenient hours. Monday-Friday 7AM-7PM and Saturday 9-12. Dr. Todd Buchanan and his family have lived in the Rochester area their entire lives (Kasson and Byron to be exact) and want to give back to the community through providing the best Chiropractic Care with their State of the Art Facility. Their new clinic provides Acupuncture, Herbal Medicine, Decompression, a Digital Motion X-Ray, Reiki, and a large classroom to be used for multiple functions including their weekly Yoga and health classes which are free for their patients.
Bluestem Center for Child and Family Development is located in a unique building designed to enhance our work and mission. Our facility was designed to recall the prairie days in Minnesota: think of it as a farmhouse. A farmhouse is a working building and also a welcoming one. It’s comfortable without being fussy. Everyone has a job to do – even the smallest children contribute by helping with dishes or looking after animals. There’s hospitality – always room for one more at a farmhouse table! The hallways are wide enough for children and families to walk side-by-side. All areas of the building have natural lighting. Particular attention was given to stairwells to make them broad and well-lit. Waiting areas are scattered throughout the building to allow families and patients some privacy. Original art and some collections are hung throughout the building, including some dramatic photos of flowers by Dr. Atkinson. Bluestem is "green." Bluestem has geo-thermal heating and cooling, which means that the building’s furnace or air-conditioning run only to boost or trim the heat a few degrees from the stable fifty degrees supplied by our below-frostline system. Windows open to save on the need for frequent thermostat adjustments. Vertical and horizontal fins outside the windows add strategic shade during sunny months. When possible, light fixtures use energy-saving bulbs and timers turn off lights that are not in use. Recycled and low-impact materials were given preference during construction. Bluestem Center is adjacent to the Zumbro River, allowing for restful views from most of the professional offices. On the river level a large conference room gives us space for staff meetings, group sessions, and teaching and opens onto a patio. A small kitchenette opens into the conference room. The conference room is available to groups by arrangement with our office manager. We have ample off-street parking. A coffee shop, bagel-sandwich shop, and Italian restaurant are close by. Plans for the future include upgrading a fallow hillside area (located to the south of the building) and the property facing the river into prairie. We’re proud of our facility! Bluestem Center was designed by Roger Nelson of HGA Architects & Engineers and built by Scheoppner Construction. We opened in October, 2004. Bluestem Center was awarded first prize for New Construction by the Rochester Committee on Urban Design and Environment in November, 2005.
Hoy en día, en el sistema de Mayo Clinic trabajan más de 3.700 médicos y científicos, aparte de un personal de apoyo de mas de 50.000 almas. Los médicos de Mayo Clinic comparten la información del paciente a través de un expediente electrónico unificado, además de normalmente recurrir a la pericia de sus colegas a fin de atender debidamente las necesidades de todos sus pacientes. Nuestros médicos son asalariados y su remuneración no depende ni de la cantidad de pacientes atendidos ni de exámenes solicitados, lo que les permite concentrarse en una sola prioridad: las necesidades del paciente.
At Mayo Clinic, there are a group of providers who are experts in the treatment of non-Hodgkin and Hodgkin lymphoma. The Lymphoma Group at Mayo Clinic offers consultations, diagnosis, treatment, and management of lymphoma. We offer a large number of new, innovative, and competitive clinical trials. Lymphoma is a cancer of the lymphatic system, the body's disease-fighting network. The lymphatic system includes the lymph nodes (lymph glands), spleen, thymus gland and bone marrow. Lymphoma can affect all those areas as well as other organs throughout the body. In order to understand the disease, it may help to first learn about lymphocytes. Lymphocytes Lymphocytes are the white blood cells affected by lymphoma. Lymphocytes are part of your immune system and travel throughout your body to fight infection. Lymphocytes can either grow too fast in an uncontrolled manner or they can live longer than normal. These abnormal lymphocytes don’t work as they should and can crowd out healthy, working cells. Types of Lymphoma Many types of lymphoma exist, with the two main types being Hodgkin's lymphoma and non-Hodgkin's lymphoma. What lymphoma treatment is best for you depends on your lymphoma type, the severity of your lymphoma and your preferences. Lymphoma treatment may involve chemotherapy, medications, radiation therapy or a stem cell transplant. Hodgkin lymphoma Hodgkin lymphoma or Hodgkin disease is a cancer of the lymphatic system. Hodgkin lymphoma is uncommon. Non-Hodgkin lymphoma, which is more common, describes another group of cancers of the lymphatic system. Hodgkin lymphoma usually starts in the lymph nodes. Hodgkin lymphoma usually presents as enlargement of the lymph nodes, but almost any organ can be involved. Non-Hodgkin lymphoma (NHL) Non-Hodgkin lymphoma (NHL) describes a group of lymphomas – it is not a single disease. The World Health Organization lists more than 33 types of lymphoma, which is the fifth most common cancer. Although different types of NHL have common characteristics, they are distinct diseases – with different manifestations, treatments and prognoses. There are two kinds of lymphocytes: B cells and T cells. NHL is divided into two large groups, depending on whether the B cells or the T cells are affected.
Chronic lymphocytic leukemia (CLL) is a type of cancer of the lymphocytes (a kind of white blood cell). It is also referred to as small lymphocytic lymphoma (SLL). CLL/SLL is one of the most common lymphoid cancers in the United States. The course of CLL/SLL varies a lot. One-third of people with CLL/SLL never need treatment, one-third doesn’t need treatment for many years, and one-third need treatment immediately. Although currently there is no cure for CLL/SLL, treatment to control the disease is available. New advances in testing make it easier to diagnose CLL/SLL earlier and to better predict how the disease will progress. However, some testing is still only available on a limited basis. If you have been diagnosed with CLL/SLL, it is best to consult with a hematologist who is experienced in diagnosing, counseling and treating the disease. If you have questions about this information or about your condition, talk with your health care provider. What is chronic lymphocytic leukemia/small lymphocytic lymphoma? CLL/SLL is a cancer of the lymphocytes (one kind of white blood cell that impacts your immune system). In order to understand CLL, it may help to learn some general information about your blood and lymphatic system. Your blood Normally, your body’s bone marrow produces stem cells that grow into different types of blood cells. Three types of mature blood cells are: • Red blood cells (erythrocytes) that carry oxygen from your lungs to all parts of your body. In order to work well, your body needs a constant supply of oxygenated blood. • Platelets that help your blood clot after a cut or an injury. • White blood cells (leukocytes) that fight infection and disease. One kind of white blood cell is a lymphocyte. There are three kinds of lymphocytes: • B lymphocytes • T lymphocytes • Natural killer cells CLL/SLL is caused when the B lymphocytes that come from a single, abnormal cell accumulate. Because of damage to their DNA, the lymphocytes grow in an uncontrolled manner and live longer than normal. The results are a higher than normal concentration of lymphocytes in the blood, bone marrow, lymph nodes and spleen. These abnormal B lymphocytes tend to crowd out other healthy blood cells; preventing them from doing their normal jobs, including fighting infections. Your lymphatic system The lymphatic system is part of your immune system and is made up of branches that go to lymph nodes all over your body. It drains body fluid (lymph) from the tissues into the veins. The lymph ducts drain lymph through the lymph nodes, which filter germs and other foreign substances. Lymphocytes and other immune system cells circulate continuously through the tissues, lymph nodes and the bone marrow. When you have an infection, the lymphocytes in the lymph nodes respond to fight the infection and prevent further spread of disease. When activated, lymph nodes can swell. Increased lymph node size also can be a sign of malignancy. Related conditions can include: Hairy cell leukemia Large granular lymphocyte disorders Lymphocytosis Natural killer cell leukemia Prolymphocytic leukemia
The different leukemias and disorders of bone marrow function : Acute lymphocytic leukemia (ALL) A type of cancer of the blood and bone marrow — the spongy tissue inside bones where blood cells are made. The word "acute" in acute lymphocytic leukemia comes from the fact that the disease progresses rapidly and creates immature blood cells, rather than mature ones. The "lymphocytic" in acute lymphocytic leukemia refers to the white blood cells called lymphocytes, which ALL affects. Acute lymphocytic leukemia is also known as acute lymphoblastic leukemia. Acute lymphocytic leukemia is the most common type of cancer in children, and treatments result in a good chance for a cure. Acute lymphocytic leukemia can also occur in adults, though the chance of a cure is greatly reduced. Acute Myeloid Leukemia (AML) A cancer of the blood and bone marrow — the spongy tissue inside bones where blood cells are made. The word "acute" in acute myelogenous leukemia denotes the disease's rapid progression. It's called myelogenous (my-uh-LOHJ-uh-nus) leukemia because it affects a group of white blood cells called the myeloid cells, which normally develop into the various types of mature blood cells, such as red blood cells, white blood cells and platelets. Acute myelogenous leukemia is also known as acute myeloid leukemia, acute myeloblastic leukemia, acute granulocytic leukemia and acute nonlymphocytic leukemia. Chronic Myelogenous Leukemia (CML) An uncommon type of cancer of the blood cells. The term "chronic" in chronic myelogenous leukemia indicates that this cancer tends to progress more slowly than acute forms of leukemia. The term "myelogenous" (my-uh-LOHJ-uh-nus) in chronic myelogenous leukemia refers to the type of cells affected by this cancer. Chronic myelogenous leukemia can also be called chronic myeloid leukemia and chronic granulocytic leukemia. Chronic myelogenous leukemia typically affects older adults and rarely occurs in children, though it can occur at any age. Myelodysplastic Syndrome (MDS) Often used to describe a group of uncommon diseases of the bone marrow and blood. MDS occurs when the stem cells in your bone marrow, which are responsible for making blood cells, do not do their job. In a myelodysplastic syndrome, stem cells may not make enough of the different types of blood cells, or the blood cells they make do not work as they should. Generally, the failure of stem cells to produce working blood cells begins gradually. Most people with MDS are 60 or older. However, MDS can affect people of any age. MDS may be an ongoing (chronic), stable condition with small changes in the blood counts over a long time, or it may quickly become life threatening. To understand MDS, it may help to understand how the stem cells and the bone marrow normally work. Normal bone marrow - Normally, your bone marrow is a blood cell factory. The stem cells in your bone marrow make the three main kinds of blood cells circulating through your body: • Red blood cells (erythrocytes) carry oxygen. • White blood cells (leukocytes) fight infection. • Platelets help the blood to clot. The stem cells make as many blood cells as your body needs. For example, if you have an infection, your stem cells make more white blood cells. Bone marrow and MDS - In MDS, something goes wrong with a stem cell. The defective stem cell makes more defective stem cells, which begin to crowd out healthy stem cells. Defective stem cells either don’t make enough healthy, mature blood cells or they make defective blood cells. Immature cells (blast cells) may pile up. Once 20 percent of the cells in the bone marrow are immature blast cells, the condition is no longer considered MDS and is instead called acute myeloid leukemia (AML). Types of myelodysplastic syndromes Myelodysplastic syndromes are a group of similar diseases that have low blood counts and a risk of progressing into AML. They have many different names, and there are different ways to describe them. They can be divided into five main types: • Refractory anemia (RA). Refractory anemia does not respond to treatment with vitamins or iron. It may be considered an “early” kind of MDS. There are no immature blast cells in the blood. In the marrow, blast counts are either normal or close to normal. • Refractory cytopenias with multilineage dysplasia (RCMD). This type of MDS is similar to refractory anemia, but instead of just anemia, other types (white blood cells, platelets) are also low. The risk of developing leukemia or a serious complication related to low blood counts are higher with RCMD than with refractory anemia, so RCMD is sometimes considered an “intermediate” kind of MDS. • Refractory anemia with excess blasts (RAEB). In RAEB, increased blasts are present in the bone marrow and some may go into the bloodstream. The higher the number of blasts, the greater the possibility RAEB will become acute leukemia. RAEB is considered a higher risk type of MDS. • Refractory anemia with ring sideroblasts (RARS). Ring sideroblasts are developing red blood cells that get their name from a dark circle caused by abnormal iron deposits. People with ring sideroblasts sometimes have too much iron in their bodies. Ring sideroblast cells can be caused by other medical conditions. Most people with RARS have anemia and not other low blood counts. • MDS associated with deletions of the long arm chromosome 5. This form of MDS is associated with an abnormal chromosome 5 that is missing part of it its long arm (called “q”). It is not inherited and is only present in bone marrow and blood cells. Anemia is common, and the platelet count may be normal or may be elevated. This form is less likely to turn into leukemia. Several variations of these five main types of MDS exist. Talk with your health care provider about your condition. There are also Myeloproliferative Neoplasms (MPN) that can include: o Polycythemia Vera (PV) (http://www.mayoclinic.org/diseases-conditions/polycythemia-vera/basics/definition/con-20031013) o Essential Thrombocythemia (ET) (http://www.mayoclinic.org/diseases-conditions/thrombocythemia/basics/definition/con-20034386) o Primary Myelofibrosis (Post ET/PV Myelofibrosis) (PMF) (http://www.mayoclinic.org/diseases-conditions/myelofibrosis/basics/definition/con-20027210) o Chronic Eosinophilic Leukemia/Hypereosinophilic Syndrome (http://www.mayoclinic.org/diseases-conditions/hypereosinophilic-syndrome/basics/definition/con-20036168) o Chronic Neutrophilic Leukemia (CNL) o Chronic Myelomonocytic Leukemia (CMML) o MDS-MPN overlap syndromes (MPN-MDS)
Mayo Clinic has Hematology specialists that evaluate and treat patients with plasma cell disorders. Monoclonal gammopathies These are disorders characterized by uncontrolled growth of plasma cells, a type of white blood cells. This results in increased levels of abnormal proteins in the blood and or urine and increased numbers of plasma cells in the bone marrow. Plasma cells normally make proteins called antibodies to help you fight infections. The majority of patients with a monoclonal gammopathy do not suffer any adverse consequence due to the increased plasma cell disorders and no treatment is necessary. However, a small number of patients can develop problems related to the increased numbers of plasma cells and will be diagnosed with multiple myeloma, amyloidosis or a related disorder. Multiple myeloma Multiple myeloma is a cancer of your plasma cells, a type of white blood cell present in your bone marrow. Plasma cells normally make proteins called antibodies to help you fight infections. In multiple myeloma, a group of plasma cells (myeloma cells) becomes cancerous and multiplies, raising the number of plasma cells to a higher than normal level. Since these cells normally make proteins (antibodies), the level of abnormal proteins in your blood also may go up. Health problems caused by multiple myeloma can affect your bones, immune system, kidneys and red blood cell count. In patients with multiple myeloma, the amount of cells in the bone marrow as well as the abnormal protein levels in the blood and urine may have increased considerably. Patients can develop high levels of calcium, low blood counts, deterioration of kidney function and destruction of bone. If you have multiple myeloma but don't have symptoms, your doctor may just monitor your condition. If you're experiencing symptoms, a number of treatments are available to help control multiple myeloma. Amyloidosis Amyloidosis (am-uh-loi-DO-sis) is a disease that occurs when substances called amyloid proteins build up in your organs. Amyloid is an abnormal protein usually produced by the plasma cells in your bone marrow that can be deposited in any tissue or organ. Amyloidosis can affect different organs in different people, and there are different types of amyloid. Amyloidosis frequently affects the heart, kidneys, liver, spleen, nervous system and gastrointestinal tract. Amyloidosis is rare, and the exact cause is often unknown. Treatments are available to help you manage your symptoms of amyloidosis and limit the production of amyloid protein. Dysproteinemia Dysproteinemia is an abnormality in protein content of the blood, usually in the content of immunoglobulins.
The Core Consultative Hematology Group evaluates and treats patients with changes in their blood counts of an undiagnosed or benign nature including: • Anemia and red cell disorders • Autoimmune hemolytic anemias • Autoimmune thrombocytopenia • Blood transfusion • Hemoglobinopathies • Hemolytic uremic syndrome • Hemophagocytic syndrome • Hereditary hemolytic anemias • Histiocytic disorders • Immune thrombocytopenia (fdkjd) Support group: • Leukopenia • Paroxysmal nocturnal hemoglobinuria • Platelet disorders • Thrombocytopenia • White blood cell disorders
To request an appointment: Arizona: 480-301-1735; Florida: 904-953-0853; Minnesota: 507-284-2511
The Priestley Society is a Mayo Alumni Association for surgeons who are currently on staff at any of the three sites, trained at Mayo, or former staff members at Mayo. The society was named for James T. Priestley, a prominent Mayo Clinic surgeon with a national and international reputation. It was founded in April 1965 by residents and fellows who worked with Dr. Priestley. He had a great deal of enthusiasm for teaching young residents the care of patients and the craft of surgery. The Priestley Society is an engaging, exciting, and stimulating Society to be a part of. Currently it consists of more than 600 members made up of Mayo surgical alumni throughout the world. We meet once a year for scientific exchange as well as for renewal of friendships at various social events. The yearly membership fee is $40.
At Mayo Clinic, there are a group of providers who are experts in the treatment of non-Hodgkin and Hodgkin lymphoma. The Lymphoma Group at Mayo Clinic offers consultations, diagnosis, treatment, and management of lymphoma. We offer a large number of new, innovative, and competitive clinical trials. Lymphoma is a cancer of the lymphatic system, the body's disease-fighting network. The lymphatic system includes the lymph nodes (lymph glands), spleen, thymus gland and bone marrow. Lymphoma can affect all those areas as well as other organs throughout the body. In order to understand the disease, it may help to first learn about lymphocytes. Lymphocytes Lymphocytes are the white blood cells affected by lymphoma. Lymphocytes are part of your immune system and travel throughout your body to fight infection. Lymphocytes can either grow too fast in an uncontrolled manner or they can live longer than normal. These abnormal lymphocytes don’t work as they should and can crowd out healthy, working cells. Types of Lymphoma Many types of lymphoma exist, with the two main types being Hodgkin's lymphoma and non-Hodgkin's lymphoma. What lymphoma treatment is best for you depends on your lymphoma type, the severity of your lymphoma and your preferences. Lymphoma treatment may involve chemotherapy, medications, radiation therapy or a stem cell transplant. Hodgkin lymphoma Hodgkin lymphoma or Hodgkin disease is a cancer of the lymphatic system. Hodgkin lymphoma is uncommon. Non-Hodgkin lymphoma, which is more common, describes another group of cancers of the lymphatic system. Hodgkin lymphoma usually starts in the lymph nodes. Hodgkin lymphoma usually presents as enlargement of the lymph nodes, but almost any organ can be involved. Non-Hodgkin lymphoma (NHL) Non-Hodgkin lymphoma (NHL) describes a group of lymphomas – it is not a single disease. The World Health Organization lists more than 33 types of lymphoma, which is the fifth most common cancer. Although different types of NHL have common characteristics, they are distinct diseases – with different manifestations, treatments and prognoses. There are two kinds of lymphocytes: B cells and T cells. NHL is divided into two large groups, depending on whether the B cells or the T cells are affected.
The different leukemias and disorders of bone marrow function : Acute lymphocytic leukemia (ALL) A type of cancer of the blood and bone marrow — the spongy tissue inside bones where blood cells are made. The word "acute" in acute lymphocytic leukemia comes from the fact that the disease progresses rapidly and creates immature blood cells, rather than mature ones. The "lymphocytic" in acute lymphocytic leukemia refers to the white blood cells called lymphocytes, which ALL affects. Acute lymphocytic leukemia is also known as acute lymphoblastic leukemia. Acute lymphocytic leukemia is the most common type of cancer in children, and treatments result in a good chance for a cure. Acute lymphocytic leukemia can also occur in adults, though the chance of a cure is greatly reduced. Acute Myeloid Leukemia (AML) A cancer of the blood and bone marrow — the spongy tissue inside bones where blood cells are made. The word "acute" in acute myelogenous leukemia denotes the disease's rapid progression. It's called myelogenous (my-uh-LOHJ-uh-nus) leukemia because it affects a group of white blood cells called the myeloid cells, which normally develop into the various types of mature blood cells, such as red blood cells, white blood cells and platelets. Acute myelogenous leukemia is also known as acute myeloid leukemia, acute myeloblastic leukemia, acute granulocytic leukemia and acute nonlymphocytic leukemia. Chronic Myelogenous Leukemia (CML) An uncommon type of cancer of the blood cells. The term "chronic" in chronic myelogenous leukemia indicates that this cancer tends to progress more slowly than acute forms of leukemia. The term "myelogenous" (my-uh-LOHJ-uh-nus) in chronic myelogenous leukemia refers to the type of cells affected by this cancer. Chronic myelogenous leukemia can also be called chronic myeloid leukemia and chronic granulocytic leukemia. Chronic myelogenous leukemia typically affects older adults and rarely occurs in children, though it can occur at any age. Myelodysplastic Syndrome (MDS) Often used to describe a group of uncommon diseases of the bone marrow and blood. MDS occurs when the stem cells in your bone marrow, which are responsible for making blood cells, do not do their job. In a myelodysplastic syndrome, stem cells may not make enough of the different types of blood cells, or the blood cells they make do not work as they should. Generally, the failure of stem cells to produce working blood cells begins gradually. Most people with MDS are 60 or older. However, MDS can affect people of any age. MDS may be an ongoing (chronic), stable condition with small changes in the blood counts over a long time, or it may quickly become life threatening. To understand MDS, it may help to understand how the stem cells and the bone marrow normally work. Normal bone marrow - Normally, your bone marrow is a blood cell factory. The stem cells in your bone marrow make the three main kinds of blood cells circulating through your body: • Red blood cells (erythrocytes) carry oxygen. • White blood cells (leukocytes) fight infection. • Platelets help the blood to clot. The stem cells make as many blood cells as your body needs. For example, if you have an infection, your stem cells make more white blood cells. Bone marrow and MDS - In MDS, something goes wrong with a stem cell. The defective stem cell makes more defective stem cells, which begin to crowd out healthy stem cells. Defective stem cells either don’t make enough healthy, mature blood cells or they make defective blood cells. Immature cells (blast cells) may pile up. Once 20 percent of the cells in the bone marrow are immature blast cells, the condition is no longer considered MDS and is instead called acute myeloid leukemia (AML). Types of myelodysplastic syndromes Myelodysplastic syndromes are a group of similar diseases that have low blood counts and a risk of progressing into AML. They have many different names, and there are different ways to describe them. They can be divided into five main types: • Refractory anemia (RA). Refractory anemia does not respond to treatment with vitamins or iron. It may be considered an “early” kind of MDS. There are no immature blast cells in the blood. In the marrow, blast counts are either normal or close to normal. • Refractory cytopenias with multilineage dysplasia (RCMD). This type of MDS is similar to refractory anemia, but instead of just anemia, other types (white blood cells, platelets) are also low. The risk of developing leukemia or a serious complication related to low blood counts are higher with RCMD than with refractory anemia, so RCMD is sometimes considered an “intermediate” kind of MDS. • Refractory anemia with excess blasts (RAEB). In RAEB, increased blasts are present in the bone marrow and some may go into the bloodstream. The higher the number of blasts, the greater the possibility RAEB will become acute leukemia. RAEB is considered a higher risk type of MDS. • Refractory anemia with ring sideroblasts (RARS). Ring sideroblasts are developing red blood cells that get their name from a dark circle caused by abnormal iron deposits. People with ring sideroblasts sometimes have too much iron in their bodies. Ring sideroblast cells can be caused by other medical conditions. Most people with RARS have anemia and not other low blood counts. • MDS associated with deletions of the long arm chromosome 5. This form of MDS is associated with an abnormal chromosome 5 that is missing part of it its long arm (called “q”). It is not inherited and is only present in bone marrow and blood cells. Anemia is common, and the platelet count may be normal or may be elevated. This form is less likely to turn into leukemia. Several variations of these five main types of MDS exist. Talk with your health care provider about your condition. There are also Myeloproliferative Neoplasms (MPN) that can include: o Polycythemia Vera (PV) (http://www.mayoclinic.org/diseases-conditions/polycythemia-vera/basics/definition/con-20031013) o Essential Thrombocythemia (ET) (http://www.mayoclinic.org/diseases-conditions/thrombocythemia/basics/definition/con-20034386) o Primary Myelofibrosis (Post ET/PV Myelofibrosis) (PMF) (http://www.mayoclinic.org/diseases-conditions/myelofibrosis/basics/definition/con-20027210) o Chronic Eosinophilic Leukemia/Hypereosinophilic Syndrome (http://www.mayoclinic.org/diseases-conditions/hypereosinophilic-syndrome/basics/definition/con-20036168) o Chronic Neutrophilic Leukemia (CNL) o Chronic Myelomonocytic Leukemia (CMML) o MDS-MPN overlap syndromes (MPN-MDS)
Mayo Clinic has Hematology specialists that evaluate and treat patients with plasma cell disorders. Monoclonal gammopathies These are disorders characterized by uncontrolled growth of plasma cells, a type of white blood cells. This results in increased levels of abnormal proteins in the blood and or urine and increased numbers of plasma cells in the bone marrow. Plasma cells normally make proteins called antibodies to help you fight infections. The majority of patients with a monoclonal gammopathy do not suffer any adverse consequence due to the increased plasma cell disorders and no treatment is necessary. However, a small number of patients can develop problems related to the increased numbers of plasma cells and will be diagnosed with multiple myeloma, amyloidosis or a related disorder. Multiple myeloma Multiple myeloma is a cancer of your plasma cells, a type of white blood cell present in your bone marrow. Plasma cells normally make proteins called antibodies to help you fight infections. In multiple myeloma, a group of plasma cells (myeloma cells) becomes cancerous and multiplies, raising the number of plasma cells to a higher than normal level. Since these cells normally make proteins (antibodies), the level of abnormal proteins in your blood also may go up. Health problems caused by multiple myeloma can affect your bones, immune system, kidneys and red blood cell count. In patients with multiple myeloma, the amount of cells in the bone marrow as well as the abnormal protein levels in the blood and urine may have increased considerably. Patients can develop high levels of calcium, low blood counts, deterioration of kidney function and destruction of bone. If you have multiple myeloma but don't have symptoms, your doctor may just monitor your condition. If you're experiencing symptoms, a number of treatments are available to help control multiple myeloma. Amyloidosis Amyloidosis (am-uh-loi-DO-sis) is a disease that occurs when substances called amyloid proteins build up in your organs. Amyloid is an abnormal protein usually produced by the plasma cells in your bone marrow that can be deposited in any tissue or organ. Amyloidosis can affect different organs in different people, and there are different types of amyloid. Amyloidosis frequently affects the heart, kidneys, liver, spleen, nervous system and gastrointestinal tract. Amyloidosis is rare, and the exact cause is often unknown. Treatments are available to help you manage your symptoms of amyloidosis and limit the production of amyloid protein. Dysproteinemia Dysproteinemia is an abnormality in protein content of the blood, usually in the content of immunoglobulins.
The Core Consultative Hematology Group evaluates and treats patients with changes in their blood counts of an undiagnosed or benign nature including: • Anemia and red cell disorders • Autoimmune hemolytic anemias • Autoimmune thrombocytopenia • Blood transfusion • Hemoglobinopathies • Hemolytic uremic syndrome • Hemophagocytic syndrome • Hereditary hemolytic anemias • Histiocytic disorders • Immune thrombocytopenia (fdkjd) Support group: • Leukopenia • Paroxysmal nocturnal hemoglobinuria • Platelet disorders • Thrombocytopenia • White blood cell disorders
Welcome to the Mayo Clinic Gift Shop, the primary retailer of Mayo Clinic logo items. Net proceeds from the Mayo Clinic Gift Shop support Mayo Clinic education and research programs. You can also visit us at the Mayo Clinic Gift Shop, Gonda Building Subway Level location within the Shops at Gonda where we carry logo and non-logo items, including books on Mayo Clinic history and health information. Our store hours are 7 a.m. to 5 p.m. Monday through Friday. Have a question about our shop and need to give us a jingle? We can be reached by phone between 7 a.m. and 5 p.m., Monday through Friday at 507-266-3320. MAYO CLINIC DOES NOT MAKE ANY EXPRESS OR IMPLIED WARRANTIES, REPRESENTATIONS OR ENDORSEMENTS WHATSOEVER (INCLUDING WITHOUT LIMITATION WARRANTIES OF TITLE OR NONINFRINGEMENT, OR THE IMPLIED WARRANTIES OF MERCHANTABILITY OR FITNESS FOR A PARTICULAR PURPOSE) WITH REGARD TO THE SERVICE OR ANY MERCHANDISE, INFORMATION OR SERVICE PROVIDED THROUGH THE SERVICE.
The Cochlear Implant (CI) Program at Mayo Clinic began in 1982. Since then, the CI program has worked with over 800 patients. Today the CI program is supported by three surgeons, six audiologists, two speech language pathologists, a neuro-psychologist, and numerous administrative support personnel. The program continues to strive for excellence both in patient care and research. Our hope is that this platform will be used to connect CI users, potential CI users, and their families. We also hope this page will allow us to broadly communicate information related to cochlear implants, such as advancements in technology, new research findings, or suggestions for improved communication. We encourage interaction, discussion, commentary, questions and suggestions for improvement. We ask that you keep your comments and posts relevant and respectful. Mayo Clinic may remove any post or ban anyone who violates these guidelines. In particular personal attacks, inappropriate language, racism, spamming and excessive posting will not be tolerated. We reserve the right to move discussions to the discussion boards on this page and to delete excessive wall postings to improve the overall visitor experience.
Mayo Clinic School of Continuous Professional Development is an accredited, not-for-profit school within Mayo Clinic College of Medicine. Mayo Clinic believes that the needs of the patient come first. Therefore, Mayo Clinic School of Continuous Professional Development maintains a commitment to and tradition of developing and maintaining distinguished educational activities to enhance and enrich your medical knowledge and improve your service to the patient.
Primary Hyperoxaluria (PH) is a condition where too much of a substance called oxalate is present in the urine. Increased oxalate in the urine can come from eating too much oxalate in foods, or from over-absorption of oxalate by the intestines due to certain diseases (called enteric hyperoxaluria). In some persons the cause of the disease is not known, but may result from changes in the way kidneys handle normal amounts of body oxalate. PH can be initially detected at all ages, from infants to people in their 70s. Type I, Type II and Type III PH are rare genetic (inherited) disorders that are present at birth. In a person with PH Type I the liver creates too little of an enzyme called alanine: glyoxylate aminotransferase, or AGT. In PH Type II, the liver is missing a different enzyme, called glyoxylate reductase (GR) or hydroxypyruvate reductase. In September 2010, collaboration among Mayo Hyperoxaluria Center and international PH researchers studying patients with marked hyperoxaluria of uncertain cause led to the discovery that it was caused by changes in a gene called DHDPSL (now named HOGA1). Patients with HOGA1 gene changes have PH type III. In all 3 types of PH very large amounts of oxalate end up in the urine and the kidneys can be damaged to the point that they quit working (renal failure). Hyperoxaluria can cause cause kidney stones. Oxalosis happens after the kidneys fail and the excess oxalate builds up in the blood, and then spreads to the eyes, bones, muscles, blood vessels, heart and other major organs. Untreated, kidney failure and oxalosis can lead to serious illness and even death. Patients most often develop the first symptoms, typically kidney stones, anywhere from birth to the mid-20s. But hyperoxaluria may go unrecognized until age 30 to 40. In some patients the first symptom is kidney failure. People who have PH can develop: • Kidney stones • Urinary tract infections (UTI) • Calcium oxalate deposits in tissues throughout the body (Oxalosis) • Kidney failure resulting in the need for dialysis • Calcification of the kidneys (nephrocalcinosis) • Blood in the urine (hematuria) • Abdominal flank or groin pain PRIMARY HYPEROXALURIA REGISTRY Because this disease is rare, many physicians have limited experience with PH patients. Therefore, the best ways to treat PH have not been well studied. For these reasons we are trying to combine all international research efforts and pool all information. As part of this effort, a PRIMARY HYPEROXALURIA REGISTRY has been established by the Rare Kidney Stone Consortium and recently funded by the National Institutes of Health. Information collected in this registry will increase clinical and research-based understanding of the disease in a manner that no single center could do alone. By making this information available to the physicians and researchers who study PH, new ideas can be tested and research progress can be made faster. We are hoping that this may lead to earlier diagnosis and better treatments for you, your family members and other people living with PH. Who can participate in the PH Registry? Everyone who has PH (Type I, Type II or Type III) can take part in the Registry. It is completely voluntary and you may decline or withdraw at any time. To participate in this Registry you will need to give permission for your medical records to be sent to the Primary Hyperoxaluria staff and they will assist you and your physician. Privacy of information The information about your health will be maintained in the registry only by your assigned number and not by your name. The information will be maintained confidential in accordance with the local privacy regulations related to medical information. What does participation in the PH Registry mean to you? Participation in the registry will not change your current relationship with your doctor. The medical information your doctor collects will be submitted to the Primary Hyperoxaluria Registry only in a de-identified form. Sharing information on Primary Hyperoxaluria will help you, your family and your doctor to get access to resources and expert care and also help medical community to understand and take better care of patients with Primary Hyperoxaluria in the future. Please contact us by phone (800-270-4637) or e-mail ([email protected]) for more information. Dawn S. Milliner, MD Mayo Clinic, Rochester John C Lieske, MD Mayo Clinic, Rochester
The MN Breast Cancer Screening Program for Underinsured Women is a breast cancer prevention initiative, born through a partnership between the Mayo Clinic and the Sage Screening Program at the Minnesota Department of Health. Program initiatives are focused in the Southeast region of Minnesota, and targeted toward women 40 years of age and older who are uninsured or underinsured (high-deductible). Initiatives are guided by Community Engagement Coordinators within the Office of Women’s Health at Mayo clinic, who seek to increase enrollment in the Sage Screening Program, a free mammography and cervical screening program for uninsured and underinsured women of Minnesota. In addition, the Community Engagement Coordinators seek to connect women with needed services, such as transportation, treatment, obtaining medical assistance, or finding a support group. Engagement Coordinators also assist women in navigating the healthcare system.
Chronic lymphocytic leukemia (CLL) is a type of cancer of the lymphocytes (a kind of white blood cell). It is also referred to as small lymphocytic lymphoma (SLL). CLL/SLL is one of the most common lymphoid cancers in the United States. The course of CLL/SLL varies a lot. One-third of people with CLL/SLL never need treatment, one-third doesn’t need treatment for many years, and one-third need treatment immediately. Although currently there is no cure for CLL/SLL, treatment to control the disease is available. New advances in testing make it easier to diagnose CLL/SLL earlier and to better predict how the disease will progress. However, some testing is still only available on a limited basis. If you have been diagnosed with CLL/SLL, it is best to consult with a hematologist who is experienced in diagnosing, counseling and treating the disease. If you have questions about this information or about your condition, talk with your health care provider. What is chronic lymphocytic leukemia/small lymphocytic lymphoma? CLL/SLL is a cancer of the lymphocytes (one kind of white blood cell that impacts your immune system). In order to understand CLL, it may help to learn some general information about your blood and lymphatic system. Your blood Normally, your body’s bone marrow produces stem cells that grow into different types of blood cells. Three types of mature blood cells are: • Red blood cells (erythrocytes) that carry oxygen from your lungs to all parts of your body. In order to work well, your body needs a constant supply of oxygenated blood. • Platelets that help your blood clot after a cut or an injury. • White blood cells (leukocytes) that fight infection and disease. One kind of white blood cell is a lymphocyte. There are three kinds of lymphocytes: • B lymphocytes • T lymphocytes • Natural killer cells CLL/SLL is caused when the B lymphocytes that come from a single, abnormal cell accumulate. Because of damage to their DNA, the lymphocytes grow in an uncontrolled manner and live longer than normal. The results are a higher than normal concentration of lymphocytes in the blood, bone marrow, lymph nodes and spleen. These abnormal B lymphocytes tend to crowd out other healthy blood cells; preventing them from doing their normal jobs, including fighting infections. Your lymphatic system The lymphatic system is part of your immune system and is made up of branches that go to lymph nodes all over your body. It drains body fluid (lymph) from the tissues into the veins. The lymph ducts drain lymph through the lymph nodes, which filter germs and other foreign substances. Lymphocytes and other immune system cells circulate continuously through the tissues, lymph nodes and the bone marrow. When you have an infection, the lymphocytes in the lymph nodes respond to fight the infection and prevent further spread of disease. When activated, lymph nodes can swell. Increased lymph node size also can be a sign of malignancy. Related conditions can include: Hairy cell leukemia Large granular lymphocyte disorders Lymphocytosis Natural killer cell leukemia Prolymphocytic leukemia
Our program offers an excellent blend of complex and common pulmonary and critical care disorders, combined with excellent teaching and supervision by world-renowned experts. There are plenty of research opportunities and resources, not only in clinical and basic sciences but also in a separate track in the science of health care delivery, education research, professionalism and ethics, and global health. The Mayo emblem, the triple shield, symbolizes the three key areas of our focus: research, patient care and education, and the fellowship's vision and mission clearly align with that. See our frequently asked questions for additional information on the program structure, available opportunities and training environment. Those who visit our department quickly notice the dedication of our faculty and the spirit of our fellows. This is a group that people want to join and emulate. Kannan Ramar, MBBS, M.D. Pulmonary and Critical Care Medicine Fellowship Director
AthensFest 2014 will be August 1st and 2nd in the Peace Plaza, Rochester, Minnesota.