McCluer South-Berkeley High School is a secondary school located at 201 Brotherton Lane in the city of Ferguson, Missouri a suburb of St. Louis. Located in the Ferguson-Florissant School District McCluer South Berkeley is the newest secondary school. MSB educates students from the cities of Cool Valley, Ferguson, Kinloch and Berkeley.The school opened in January 2004, replacing Berkeley High School in Berkeley, which had closed in December 2003 due to expansion of the Lambert-St. Louis International Airport.